It's probably no surprise that patients with more complications generally do worse and are tougher to salvage when things go wrong...but, that said, here's a unique paper (and visual abstract) that highlight how more complications (up to three or more) correlate with increased Failure To Rescue (FTR).  

The authors (Massarweh et al) note that this holds despite risk adjustment for probability of mortality...take a minute and decide whether the technique of risk adjustment here rules out the possibility that sicker patients just do worse.  (After all, sicker patients in many cases are probably more prone to complications, have less physiologic reserve, and of course are less likely to be rescued.)

So, with work like this, take a moment to look beyond the abstract and decide if the model adjusts for the level of patient disease at the onset.

All of that said, this work interestingly highlights how Failure To Rescue is more likely in patients with more than one complication.  Watch out for that group for sure!

More on FTR, this time from the NHS, in a fascinating piece here.

Click the link below for the abstract of Massarweh et al 's paper in Annals of Surgery, and note that the visual abstract beneath is their work as well.  Citations as beneath!